What data is included?
Open PHACTS brings together the data sources you already use, including ChEBI, ChEMBL, ChemSpider, ConceptWiki, DisGeNET, DrugBank, Gene Ontology, neXtProt, UniProt and WikiPathways. Through Open PHACTS, you have access to all of this data in a single, integrated infrastructure.
Metadata about data provenance is also integrated into the Open PHACTS Discovery Platform, so you can always verify exactly where the information you see comes from.
You can access this data through the Open PHACTS Open PHACTS Explorer, other Applications, and integrate it into your Workflows.
The complete list of data sources currently integrated by Open PHACTS is as follows:
Chemical compounds from these sources are validated and normalised through the Open PHACTS Chemical Registry, which also integrates identifiers and adds synonyms from ChemSpider. Physicochemical properties are predicted by the ACD/Labs Percepta Platform.
Using the Open PHACTS Discovery Platform interfaces, anyone may access, interact with and analyse all Open PHACTS datasets for the purposes of research and development. We have confirmed with the licence holders that this includes the development and commercialisation of pharmaceuticals.
It depends on the dataset licence. Data integrated by Open PHACTS retains the licensing of the original data resources, as listed above, with two exceptions:
DrugBank data is available under a CC-BY-NC 4.0 licence. The datasets can be used freely in a non-commercial application or project. If you are interested in using DrugBank data in a commercial product or application, please see the Drugbank release page
ChemSpider and the ACD/Labs property predictions are available under a CC-BY-SA 4.0 licence
Some datasets may therefore be downloaded from Open PHACTS in their entirety, but others may not. Some licences also restrict what you may do with datasets you have downloaded. It is your responsibility to make sure that you comply with all licence terms. We recommend taking a close look at the licensing terms and conditions of any datasets you are interested in.