About Open PHACTS
What is Open PHACTS?
To reduce the barriers to drug discovery in industry, academia and for small businesses, the Open PHACTS consortium is building the Open PHACTS Discovery Platform. This will be freely available, integrating pharmacological data from a variety of information resources and providing tools and services to question this integrated data to support pharmacological research.
It is a 3-year project ending in March 2014.
What will the project deliver?
The project will deliver an online platform with a set of integrated publicly available pharmacological data. The software and data will be available for download and local installation, under an open source and open access model. Tools and services will be provided to query and visualise this data, and a sustainability plan will be in place, continuing the operation of the Open PHACTS Discovery Platform after the project funding ends.
Throughout the project, a series of recommendations will be developed in conjunction with the community, building on open standards, to ensure wide applicability of the approaches used for integration of data.
The Open PHACTS Discovery Platform is a specific achievable result from this project, but the semantic technology and principles are deliberately being adopted to enable the platform to be adapted for application to other subject domains in the future.
Who is participating in the Open PHACTS consortium?
This 3-year knowledge management project of the Innovative Medicines Initiative (IMI) is a unique partnership between the European Community and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The Open PHACTS consortium comprises of 28 partners from a wide range of backgrounds (Academia, Pharma and Biotech companies) combining expertise in pharmacology, nanopublications, semantic technology, text mining, as well as bio- and cheminformatics. See our Consortium page for further information.
Working with the community and how to get involved
The Open PHACTS project has a wide community of potential data sources, data consumers, and service providers. See our How to get involved page for details.
Key papers to cite the project
- To cite the project: Williams A., Harland L., Groth P,. et al.: Open PHACTS: Semantic interoperability for drug discovery. Drug Discovery Today, June 06, 2012
- To cite the Open PHACTS Discovery Platform: Gray A., Groth P., Loizou A., et al.: Applying Linked Data Approaches to Pharmacology: Architectural Decisions and Implementation. Semantic Web Journal, April 18, 2012