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 2012

Anna Hersey, Stefan Senger, John P Overington: Open data for drug discovery: learning from the biological community. Future Medicinal Chemistry, Volume 4, No. 15, 2012, Pages 1865-1867 read

 

 07.12.2012

Laura Furlong: Human diseases through the lens of network biology. Trends in Genetics, Science Online, Volume 29, Issue 3, March 2013, Pages 150-159 read


 19.10.2012

Christian Brenninkmeijer, Chris Evelo, Carole Goble, Alasdair J G Gray, Andra Waagmeester, Egon Willighagen: Dataset Descriptions for the Open Pharmacological Space. read


 04.10.2012

Frank van Harmelen, George Kampis, Katy Borner, Peter van den Besselaar, Erik Schultes, Carole Goble, Paul Groth, Barend Mons, Stuart Anderson, Stefan Decker, Conor Hayes, Thierry Buecheler, Dirk Helbing: Theoretical and technological building blocks for an innovation accelerator. 4 October 2012 read


25.09.2012

Lee Harland: Open PHACTS: A semantic knowledge infrastructure for public and commercial drug discovery research. Springer, Lecture Notes in Computer Science, Volume 7603, p. 1-7, 2012 read


30.08.2012

Jessica Brothwood: Druggable and biopharmable genome annotation pipeline development. MSc Thesis, Cranfield University, GlaxoSmithKine, September 2012 read


 23.08.2012

Carina Haupt, Andra Waagmeester, Marc Zimmerman, Egon Willighagen: Guidelines for exposing data as RDF in Open PHACTS, 23 August 2012 read


 15.08.2012

Molecular Informatics: Special Issue: Open Innovation in Drug Discovery. Volume 31, Issue 8, p. 517-609, August 2012 read

Gerhard F. Ecker, Bryn Williams-Jones: Open Innovation in Drug Discovery. Molecular Informatics, Volume 31, Issue 8, p. 519-520, 15 August 2012 read

Barbara Zdrazil, Niklas Blomberg, Gerhard F. Ecker: Taking Open Innovation to the Molecular Level – Strengths and Limitations. Molecular Informatics, Volume 31, Issue 8, p. 528–535, 7 August 2012 read

Maria C. Carrascosa, Oriol L. Massaguer, Jordi Mestres: PharmaTrek: A Semantic Web Explorer for Open Innovation in Multitarget Drug Discovery. Molecular Informatics, Volume 31, Issue 8, p. 537–541, 7 August 2012 read

Katrin Stierand, Tim Harder, Thomas Marek, Matthias Hilbig, Christian Lemmen, Matthias Rarey: The Internet as Scientific Knowledge Base: Navigating the Chem-Bio Space. Molecular Informatics, Volume 31, Issue 8, p. 543–546, 7 August 2012 read

Marta Pinto, Michael Trauner, Gerhard F. Ecker: An In Silico Classification Model for Putative ABCC2 Substrates. Molecular Informatics, Volume 31, Issue 8, p. 547–553, 9 August 2012 read

Mats Eriksson, Ingemar Nilsson, Thierry Kogej, Christopher Southan, Martin Johansson, Christian Tyrchan, Sorel Muresan, Niklas Blomberg, Marcus Bjäreland: SARConnect: A Tool to Interrogate the Connectivity Between Proteins, Chemical Structures and Activitiy Data. Molecular Informatics, Volume 31, Issue 8, p. 555–568, 7 August 2012 read

Alex M. Clark, Sean Ekins, Antony J. Williams: Redefining Cheminformatics with Intuitive Collaborative Mobile Apps. Molecular Informatics, Volume 31, Issue 8, p. 569–584, 4 July 2012 read

Alex M. Clark, Sean Ekins, Antony J. Williams: Open Drug Discovery Teams: A Chemistry Mobile App for Collaboration. Molecular Informatics, Volume 31, Issue 8, p. 585–597, 6 August 2012 read

Barbara Zdrazil, Marta Pinto, Poongavanam Vasanthanathan, Antony J. Williams, Linda Zander Balderud, Ola Engkvist, Christine Chichester, Anne Hersey, John P. Overington, Gerhard F. Ecker: Annotating Human P-Glycoprotein Bioassay Data. Molecular Informatics, Volume 31, Issue 8, p. 599–609, 7 August 2012 read


23.07.2012

George P. Patrinos, David N. Cooper, Erik van Mulligen, Vassiliki Gkantouna, Giannis, Tzimas, Zuotian Tatum, Erik Schultes, Marco Roos, Barend Mons: Microattribution and nanopublication as means to incentivize the placement of human genome variation data into the public domain. Human Mutation, Volume 33, Issue 11, pages 1503-1512, November 2012 read


06.06.2012

Antony J. Williams, Lee Harland, Paul Groth, Stephen Pettifer, Christine Chichester, Egon L. Willighagen, Chris T. Evelo, Niklas Blomberg, Gerhard Ecker, Carole Goble, Barend Mons: Open PHACTS: Semantic interoperability for drug discovery. Drug Discovery Today, Volume 17, Issues 21-22, November 2012, pages 1188-1198 read   (key paper to cite the project)
 


29.05.2012

Alasdair J. G. Gray, Sune Askjaer, Christian Brenninkmeijer, Kees Burger, Christine Chichester, James Eales, Chris T. Evelo, Carole Goble, Paul Groth, Lee Harland, Antonis Loizou, Steve Pettifer, Rishi Ramgolam, Mark Thompson, Andra Waagmeester, Antony J. Williams: The Pharmacology Workspace: A Platform for Drug Discovery. Demonstration paper for ICBO 2012 - 3rd International Conference on Biomedical Ontology at University of Graz, Austria, July 21-25, 2012 read


10.05.2012

Raymond Dalgleish, Eva Molero, Richard Kidd, Mascha Jansen, Daniela Past, Anika Robl, Barend Mons, Carlos Diaz, Albert Mons, Anthony J Brookes: Solving Bottlenecks in Data Sharing in the Life Siences. Meeting Report, Human Mutation, Volume 33, Issue 10, pages 1494-1496, October 2012 read


01.05.2012

David J. Wild, Ying Ding, Amit P. Sheth, Lee Harland, Eric M. Gifford, Michael S. Lajiness: Systems chemical biology and the Semantic Web: what they mean for the future of drug discovery research. Drug Discovery Today, Volume 17, Numbers 9/10, May 2012 read


18.04.2012

Alasdair J. G. Gray, Paul Groth, Antonis Loizou, Sune Askjaer, Christian Brenninkmeijer, Kees Burger, Christine Chichester, Chris T. Evelo, Carole Goble, Lee Harland, Steve Pettifer, Mark Thompson, Andra Waagmeester, Antony J. Williams: Applying Linked Data Approaches to Pharmacology: Architectural Decisions and Implementation. Semantic Web Journal, 18 April 2012 read (key paper to cite the Open PHACTS Discovery Platform)
 


08.03.2012

Antony J. Williams, Sean Ekins, Valery Tkachenko: Towards a gold standard: regarding quality in public domain chemistry databases and approaches to improving the situation. Drug Discovery Today, Volume 17, Issues 13-14, Pages 685-701, July 2012 read


01.03.2012

M Goldman: The Innovative Medicines Initiative: A European Response to the Innovation Challenge. Clinical pharmacology & Therapeutics, Volume 91, Number 3, March 2012 read


30.01.2012

Antony J. Williams: It's all about the data: an exclusive interview with Dr. Antony J. Williams. Life Science Trends 2012, p. 23, January 2012 read


27.01.2012

Susanna-Assunta Sansone, Philippe Rocca-Serra, Dawn Field, Eamonn Maguire, Chris Taylor, Oliver Hofmann, Hong Fang, Steffen Neumann, Weida Tong, Linda Amaral-Zettler, Kimberly Begley, Tim Booth, Lydie Bougueleret, Gully Burns, Brad Chapman, Tim Clark, Lee-Ann Coleman, Jay Copeland, Sudeshna Das, Antoine de Daruvar, Paula de Matos, Ian Dix, Scott Edmunds, Chris T Evelo, Mark J Forster, Pascale Gaudet, Jack Gilbert, Carole Goble, Julian L Griffin, Daniel Jacob, Jos Kleinjans, Lee Harland, Kenneth Haug, Henning Hermjakob, Shannan J Ho Sui, Alain Laederach, Shaoguang Liang, Stephen Marshall, Annette McGrath, Emily Merrill, Dorothy Reilly, Magali Roux, Caroline E Shamu, Catherine A Shang, Christoph Steinbeck, Anne Trefethen, Bryn Williams-Jones, Katherine Wolstencroft, Ioannis Xenarios, Winston Hide: Toward interoperable bioscience data. Nature Genetics 44, p. 121-126, 27 January 2012 read